NATIVE
Catalog no.: AP1002AG.1 / AP1002AG.2
Name: Human Laminin 5; Laminin 5 consists of three chains: α3, β3, γ2
Synonyms: Laminin-332
MW: ~ 430 kDa
Swiss-Prot No: Q16787, Q13751, and Q13753
Gene Information: Gene Names: LAMA3, LAMB3, and LAMC2
GenelD'S: 3909, 3914, and 3918
Source: Human foreskin keratinocytes (cell culture supernatant)
Purification: Affinity chromatography
Storage buffer: 150 mM NaCl, 10 mM Tris, pH 7.4
Purity: > 90 % (SDS-PAGE)
Contents: 10 μg / 100 μg (liquid)
Store at: - 20°C
Repeated thawing and freezing must be avoided
References:
1. Tsunenaga M, Adachi E, Amano S, Burgeson RE, Nishiyama T (1998). Laminin 5 can promote assembly of the lamina densa in the skin equivalent model. Matrix Biology 17(8-9): 603-613.
2. Sercu S, Zhang M, Oyama N, Hansen U, Ghalbzouri AE, Jun G, Geentjens K, Zhang L, Merregaert JH (2008). Interaction of extracellular matrix protein 1 with extracellular matrix components: ECM1 is a basement membrane protein of the skin. J Invest Dermatol 128(6): 1397-1408.
3. Oh J-E, Jang DH, Kim H, Kang HK, Chung C-P, Park WH, Min B-M (2009). [alpha]3[beta]1 integrin promotes cell survival via multiple interactions between 14-3-3 isoforms and proapoptotic proteins. Experimental Cell Research 315(18): 3187-3200.
4. Rezvani HR, Ali N, Serrano-Sanchez M, Dubus P, Varon C, Ged C, Pain C, Cario-Andre M, Seneschal J, Taieb A, de Verneuil H, Mazurier F (2011). Loss of epidermal hypoxia-inducible factor-1 alpha accelerates epidermal aging and affects re-epithelialization in human and mouse. J Cell Sci 124(Pt 24): 4172-4183.
For research use only
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