ANTIBODY, POLYCLONAL
Catalog no.: A 8024.1 / A 8024.2
Immunogen: Synthetic human Urotensin Il, bTG conjugated (ETPDCFWKYCV)
Synonyms: Urotensin-2
Swiss-Prot No: O95399
Gene Information: Gene Name: UTS2
GenelD: 10911
Host: Rabbit
Matrix: Serum
Specificity: Synthetic human Urotensin II peptide
There was no cross reactivity obtained with human Endothelin (aa 1-21) (< 0,1%), human big Endothelin (aa 1-38) (< 0,1 %), human Urodilatin, human ANP (aa 1-28) (< 0,1%), human BNP (aa 1-32) (< 0,1%), Adrenomedulin (aa 1-52) (< 0,1%), Relaxin (< 0,1%), and Somatostatin (< 0,1%).
Contents: 20 μl / 100 μl (lyophilized)
Resuspend in 20 μl / 100 μl aqua bidest.
Known applications: ELISA (1:3000)1, 2, 3
This antibody has not been tested for use in all applications. This does not necessarily exclude its use for non-tested procedures. The stated dilutions are recommendations only. We suggest that the applicant titrates the antibody in his/her system using appropriate negative/positive controls.
Store at: 2-8 °C (lyophilized); - 20 °C (dissolved)
Repeated thawing and freezing must be avoided
References:
1. Heller J, Schepke M, Neef M, Woitas R, Rabe C, Sauerbruch T (2002). Increased urotensin II plasma
levels in patients with cirrhosis and portal hypertension. J Hepatol 37:767-72.
2. Dschietzig T, Bartsch C, Pregla R, Zurbrugg HR, Armbruster FP, Richter C et al (2002). Plasma levels
and cardiovascular gene expression of urotensin-ll in human heart failure. 1. Regul Pept 110:33-8.
3. Dschietzig T, Richter C, Bartsch C, Bohme C, Heinze D, Ott F et al (2001). Flow-induced pressure
differentially regulates endothelin-1, urotensin II, adrenomedullin, and relaxin in pulmonary vascular
endothelium. Biochem Biophys Res Commun 289:245-51.
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