ANTIBODY, POLYCLONAL
Catalog no.: AP1005.1 / AP1005.2
Immunogen: Recombinant human epidermal Transglutaminase (TGe)
Synonyms: Protein-glutamine gamma-glutamyltransferase E, EC=2.3.2.13, Transglutaminase E, Transglutaminase-3
Swiss-Prot No: Q08188
Gene Information: Gene Name: TGM3
GeneID: 7053
Host: Rabbit
Matrix: Serum
Specificity: Human Epidermal Transglutaminase (TGe)
There was no crossreactivity obtained with human Transglutaminase-1 or factor XIIIa. Crossreactivity with Transglutaminase-2 was <1%.
Contents: 20 μl / 100 μl (lyophilized)
Resuspend in 20 μl / 100 μl aqua bidest.
Known applications: ELISA1, immunohistochemistry (cryosections, 1:100-3200)1, 2, 3
This antibody has not been tested for use in all applications. This does not necessarily exclude its use in non-tested procedures. The stated dilutions are recommendations only. End users should determine optimal dilutions in their system using appropriate negative/positive controls.
Store at: 2-8 °C (lyophilized); -20 °C (dissolved)
Repeated thawing and freezing must be avoided
References:
1. Sardy M, Karpati S, Merkl B, Paulsson M, Smyth N (2002). Epidermal transglutaminase (TGase 3) is the autoantigen of dermatitis herpetiformis. J Exp Med 195(6): 747-757.
2. Oji V, Hautier JM, Ahvazi B, Hausser I, Aufenvenne K, Walker T, Seller N, Steijlen PM, Küster W, Hovnanian A, Hennies HC, Traupe H (2006). Bathing suit ichthyosis is caused by transglutaminase-1 deficiency: evidence for a temperature-sensitive phenotype. Human Molecular Genetics 15(21): 3083-3097.
3. Cannistraci C, Lesnoni La Parola I, Cardinali G, Bolasco G, Aspite N, Stigliano V & Picardo M (2007). Co-localization of IgA and TG3 on healthy skin of coeliac patients. J. Eur. Acad. Dermatol. Venereol. 21: 509-14.
For research use only
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