ANTIBODY, POLYCLONAL
Catalog no.: A 8101.1 / A 8101.2
Immunogen: Succinyl cGMP-human serum albumin conjugate
Synonyms: Cyclic guanosine monophosphate
Host: Rabbit
Matrix: Serum
Specificity: cGMP
Cross-reactivity at 50 % displacement: cAMP < 0.0005 %, GTP < 0.00001 %, ATP < 0.00001 %
Contents: 20 μl / 100 μl (lyophilized)
Resuspend in 20 μl / 100 μl aqua bidest.
Known applications: RIA1, 2, 3
Antigen binding capacity: Dilutions 1/2000 bound 45-50 % of the labelled (radioactive) nucleotide.
This antibody has not been tested for use in all applications. This does not necessarily exclude its use for non-tested procedures. The stated dilutions are recommendations only. We suggest that the applicant titrates the antibody in his/her system using appropriate negative/positive controls.
Store at: 2-8 °C (lyophilized); - 20 °C (dissolved)
Repeated thawing and freezing must be avoided
References:
1. Defagot C, Zubin P (1994). Preparation, production and functional characterization of anti cAMP and cGMP antibodies. Biol. Res 27: 193-197.
2. Zubin P, Defagot C. Parlanti G (1995). Guanylate Cyclase Activity In the Inner Ear and Auditory Nerve of the Rat. J. Biochem, 118: 418-421.
3. Defagot C, Zubin P (1997). Effect of different illumination conditions and ionic environment on the guanylate cylase activity in retina, optic nerve and optic chiasm of the rat. J. Physiology (Paris) 91: 91-95.
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